Audience

Structural biology researchers who need fast, high-resolution protein structure prediction from sequence for analysis, exploration, and experimental planning

About ESMFold2

ESMFold2 is the successor to ESMFold, setting a new state of the art for single-sequence structure prediction and enabling the generation of new functional proteins through searching the ESMC model’s latent space. The model predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequence, with optional multiple sequence alignment input for enhanced accuracy on challenging targets. It is designed for structure prediction using sequence and structure modalities, with ESM representations powering a series of looped folding layers and a diffusion model projecting pairwise representations to atomic-resolution predictions. ESMFold2 predicts protein structures directly from amino acid sequences and outputs comprehensive structural information, including all-atom coordinates for backbone and side chains, confidence metrics, and optional distogram predictions for detailed structural analysis.

Pricing

Starting Price:
Free
Free Version:
Free Version available.

Integrations

API:
Yes, ESMFold2 offers API access

Ratings/Reviews

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Company Information

Biohub
Founded: 2016
United States
biohub.ai/models/esmfold2

Videos and Screen Captures

ESMFold2 Screenshot 1
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Product Details

Platforms Supported
Cloud
Training
Documentation
Support
Online

ESMFold2 Frequently Asked Questions

Q: What kinds of users and organization types does ESMFold2 work with?
ESMFold2 works with these users and organization types: Mid Size Business, Small Business, Enterprise, Freelance, Nonprofit, Government, and Startup.
Q: What languages does ESMFold2 support in their product?
ESMFold2 supports these languages: English.
Q: What kind of support options does ESMFold2 offer?
ESMFold2 offers support via online.
Q: What other applications or services does ESMFold2 integrate with?
ESMFold2 integrates with: Biohub, Mira, and Python.
Q: Does ESMFold2 have an API?
Yes, ESMFold2 has an API.
Q: What type of training does ESMFold2 provide?
ESMFold2 provides training in the form of documentation.
Q: How much does ESMFold2 cost?
Pricing for ESMFold2 starts at Free.

ESMFold2 Product Features